Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502990 | 0.88 | DHODH (0.77) | DHODHMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3914884 | 0.80 | DHODH (0.78) | DHODHJMJD7NR4A1NR4A2NR4A3 | |
| SCHEMBL19417217 | 0.78 | DHODH (0.70) | DHODHMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3924749 | 0.76 | DHODH (0.72) | DHODHMEN1KMT2AJMJD7NR4A1 | |
| SCHEMBL3926145 | 0.76 | DHODH (0.82) | DHODHMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL503290 | 0.75 | DHODH (1.00) | DHODHJMJD7NR4A1NR4A2NR4A3 | |
| SCHEMBL3924727 | 0.75 | DHODH (0.84) | DHODHJMJD7NR4A1NR4A2NR4A3 | |
| SCHEMBL4389419 | 0.74 | DHODH (0.68) | DHODHJMJD7NR4A1NR4A2NR4A3 | |
| SCHEMBL19417218 | 0.72 | DHODH (0.52) | DHODHMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL252179 | 0.72 | DHODH (0.83) | DHODHJMJD7NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588446-B1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2015-09-09 | — | — | EP | disclosed |