Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203377 | 0.90 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5202705 | 0.83 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5204224 | 0.83 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5207784 | 0.83 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5205543 | 0.82 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5205619 | 0.82 | HRH3 (1.00) | HRH3 | |
| SCHEMBL5203493 | 0.81 | HRH3 (1.00) | HRH3 | |
| SCHEMBL12099910 | 0.80 | HRH3 (0.63) | HRH3 | |
| SCHEMBL5203315 | 0.80 | HRH3 (1.00) | HRH3 | |
| SCHEMBL20590340 | 0.79 | HRH3 (0.54) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195307-B1 | PIPERAZINE DERIVATIVE HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LTD (GB) | 2012-04-18 | — | — | EP | claimed |