Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070454 | 0.96 | TSHR (0.36) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17484455 | 0.94 | TSHR (0.40) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17070477 | 0.93 | TSHR (0.34) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17070466 | 0.90 | TSHR (0.38) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17070462 | 0.89 | TSHR (0.33) | TNKS2TSHRPOLBAPEX1HTT | |
| SCHEMBL17070457 | 0.89 | TSHR (0.33) | TNKS2TSHRPOLBAPEX1HTT | |
| SCHEMBL17484392 | 0.89 | TSHR (0.40) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17070450 | 0.89 | TSHR (0.34) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17484454 | 0.88 | RARB (0.36) | TNKS2TSHRCYP4A11CYP4F2POLB | |
| SCHEMBL17070464 | 0.86 | TSHR (0.38) | TNKS2TSHRCYP4A11CYP4F2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730590-A1 | LIQUID CRYSTAL MEDIA WITH HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-2918658-B1 | Liquid crystalline media with homeotropic alignment | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| US-10513657-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-12-24 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-2918658-A2 | Liquid crystalline media with homeotropic alignment | Merck Patent GmbH (DE) | 2015-09-16 | — | — | EP | disclosed |
| US-20150252265-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20150252265-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |