Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL17072174

N.O=C(O)C1NCCC1=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.50
TSHR P16473 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MAPKAPK2 P49137 10/20 0.40
MAPKAPK5 Q8IW41 1/20 0.34
SLC1A2 P43004 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30
GABRA4 P48169 1/20 0.30
GABRE P78334 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668162 0.98
SCHEMBL1162329 0.98
SCHEMBL27585894 0.98 GRIA2 (0.52) GRIA2TSHRNPSR1MAPKAPK2MAPKAPK5
SCHEMBL1162649 0.98
SCHEMBL27889464 0.95 GRIA2 (0.50) GRIA2TSHRNPSR1MAPKAPK2MAPKAPK5
SCHEMBL28022606 0.95 GRIA2 (0.50) GRIA2TSHRNPSR1MAPKAPK2MAPKAPK5
SCHEMBL27889463 0.95 GRIA2 (0.50) GRIA2TSHRNPSR1MAPKAPK2MAPKAPK5
SCHEMBL6641445 0.84 GRIA2 (0.44) GRIA2TSHRNPSR1MAPKAPK2
SCHEMBL1849832 0.84 GRIA2 (0.44) GRIA2TSHRNPSR1MAPKAPK2
Proline SCHEMBL28049888 0.82 GRIA2 (0.41) GRIA2TSHRNPSR1MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9132111-B2 Topical antimicrobial compositions LU KEWANG (US) 2015-09-15 US claimed