SCHEMBL17073586

SCHEMBL17073586

Clc1cccc(-c2nc(C3=CCCC=C3)cc(-c3ccccc3)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.45
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
ALDH1A1 P00352 5/20 0.42
HPGD P15428 5/20 0.42
MAPT P10636 4/20 0.42
KDM4E B2RXH2 3/20 0.42
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NR1I3 Q14994 1/20 0.40
VCP P55072 1/20 0.40
IDH1 O75874 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
NTSR1 P30989 1/20 0.38
DPP4 P27487 1/20 0.38
HRH4 Q9H3N8 1/20 0.38
ABCG2 Q9UNQ0 2/20 0.37
PDE5A O76074 2/20 0.37
ABCB1 P08183 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19526947 0.97 ADORA1 (0.43) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL17073591 0.91 ADORA1 (0.46) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL22073300 0.85 NR1I3 (0.41) ADORA1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL17033540 0.85 MEN1 (0.61) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL15871198 0.85 MEN1 (0.43) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL23723139 0.84 MEN1 (0.42) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL22812610 0.84 NR1I3 (0.40) ADORA1MEN1KMT2AMAPTKDM4E
SCHEMBL16442531 0.84 MAPT (0.42) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL27255922 0.83 MEN1 (0.41) ADORA1MEN1KMT2AALDH1A1HPGD
SCHEMBL23033831 0.81 MAPT (0.44) ADORA1MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015133804-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-09-11 WO disclosed