Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707685 | 1.00 | KAT2B (0.49) | KAT2BKDM4EKMT2AHDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL1707465 | 0.99 | KAT2B (0.49) | KAT2BKDM4EKMT2AHDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL1707463 | 0.99 | KAT2B (0.49) | KAT2BKDM4EKMT2AHDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL5192487 | 0.95 | HDAC1 (0.48) | KAT2BHDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL4223260 | 0.95 | HDAC1 (0.48) | KAT2BHDAC1HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL4223253 | 0.95 | HDAC1 (0.48) | KAT2BHDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL1708336 | 0.92 | KAT2B (0.51) | KAT2BKDM4EKMT2ASIGMAR1CHRNB2 | |
| SCHEMBL1708335 | 0.92 | KAT2B (0.51) | KAT2BKDM4EKMT2ASIGMAR1CHRNB2 | |
| SCHEMBL4217268 | 0.90 | HDAC1 (0.53) | HDAC1HDAC8HDAC6SIGMAR1HDAC3 | |
| SCHEMBL5169589 | 0.90 | HDAC1 (0.53) | HDAC1HDAC8HDAC6SIGMAR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | claimed |
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |