Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | JUN | P05412 | 1/20 | 0.68 |
| ▸ | MME | P08473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.68 |
| ▸ | XDH | P47989 | 4/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | NQO1 | P15559 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17077382 | 1.00 | EGFR (1.00) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL17077384 | 0.95 | EGFR (0.90) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL17077386 | 0.95 | EGFR (0.90) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL17077399 | 0.90 | EGFR (1.00) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL17077396 | 0.90 | EGFR (1.00) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL17077347 | 0.84 | EGFR (1.00) | EGFRNFE2L2XDHCYP1A2CYP2C9 | |
| SCHEMBL17077345 | 0.84 | EGFR (1.00) | EGFRNFE2L2XDHCYP1A2CYP2C9 | |
| SCHEMBL17077357 | 0.84 | EGFR (0.90) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL17077360 | 0.84 | EGFR (0.90) | EGFRNFE2L2MEN1KMT2AJUN | |
| SCHEMBL1524276 | 0.84 | EGFR (0.72) | EGFRMEN1KMT2AJUNMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409845-B2 | Alpha-(3,5-dimethoxybenzylidene)-alpha′-hydrocarbyl methylene cyclic ketone and preparation method thereof | PHARMAXYN LABORATORIES LTD. (CN) | 2016-08-09 | — | — | US | disclosed |
| EP-2927208-A1 | A-(3,5-DIMETHOXY BENZYLIDENE)-A'-HYDROCARBYL METHYLENE CYCLIC KETONE AND PREPARATION METHOD THEREOF | Pharmaxyn Laboratories Ltd. (CN) | 2015-10-07 | — | — | EP | disclosed |
| US-20150259271-A1 | alpha-(3,5-dimethoxybenzylidene)-alpha'-hydrocarbyl methylene cyclic ketone and preparation method thereof | PHARMAXYN LABORATORIES LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259271-A1 | alpha-(3,5-dimethoxybenzylidene)-alpha'-hydrocarbyl methylene cyclic ketone and preparation method thereof | EGFR, KDR, BMI1 | EGFR 1/4885NFE2L2 50/4885MEN1 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.