Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768409 | 0.80 | PIM1 (0.33) | PIM1 | |
| SCHEMBL2363850 | 0.72 | TNKS (0.34) | — | |
| SCHEMBL17335930 | 0.72 | TNKS (0.34) | — | |
| SCHEMBL17078065 | 0.68 | — | — | |
| SCHEMBL28816058 | 0.65 | — | — | |
| SCHEMBL17078088 | 0.64 | — | — | |
| SCHEMBL14244355 | 0.63 | — | — | |
| SCHEMBL5552556 | 0.62 | — | — | |
| SCHEMBL14285871 | 0.61 | PIM1 (0.32) | PIM1 | |
| SCHEMBL3982749 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015135091-A1 | PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-09-17 | — | — | WO | disclosed |