Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10008962 | 0.93 | FFAR1 (0.38) | FFAR1MAPTKMT2APPARGPPARD | |
| SCHEMBL10008963 | 0.93 | FFAR1 (0.38) | FFAR1MAPTKMT2APPARGPPARD | |
| SCHEMBL1708211 | 0.89 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL1707796 | 0.84 | FFAR1 (0.36) | FFAR1PPARGPPARD | |
| SCHEMBL10009833 | 0.84 | AKR1C3 (0.41) | FFAR1PPARGPPARD | |
| SCHEMBL10009839 | 0.84 | AKR1C3 (0.41) | FFAR1PPARGPPARD | |
| SCHEMBL10009327 | 0.83 | PPARG (0.36) | FFAR1PPARGPPARD | |
| SCHEMBL10009325 | 0.83 | PPARG (0.36) | FFAR1PPARGPPARD | |
| SCHEMBL1707831 | 0.82 | NPC1 (0.34) | MAPTSMN1; SMN2KMT2AKCNMA1NPC1 | |
| SCHEMBL10011798 | 0.82 | FFAR1 (0.40) | FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |