SCHEMBL1707888

SCHEMBL1707888

O=C(O)CC(C(=O)O)C(OC(=O)C(O)C(O)C(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
PGD P52209 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10878073 0.91 TDP1 (0.48) TDP1SMN1; SMN2SLC22A6MMP1MMP2
SCHEMBL9995363 0.83 TDP1 (0.48) TDP1SMN1; SMN2SLC22A6MMP1MMP2
SCHEMBL1289946 0.80 TDP1 (0.45) TDP1TSHRSMN1; SMN2SLC22A6MMP1
SCHEMBL27944171 0.80 TSHR (0.53) TSHRMMP1MMP2MMP3MMP9
SCHEMBL184960 0.78 TSHR (0.50) TSHRMMP1MMP2MMP3MMP9
SCHEMBL27553498 0.78 TSHR (0.50) TSHRMMP1MMP2MMP3MMP9
SCHEMBL2200092 0.78 TSHR (0.50) TSHRMMP1MMP2MMP3MMP9
SCHEMBL5691239 0.78 TSHR (0.50) TSHRMMP1MMP2MMP3MMP9
SCHEMBL5691242 0.78 TSHR (0.50) TSHRMMP1MMP2MMP3MMP9
SCHEMBL8145944 0.78 TSHR (0.50) TSHRMMP1MMP2MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1755003-B1 Stripper ROHM & HAAS ELECT MAT (US) 2012-04-18 EP claimed
US-7723280-B2 Stripper for electronics ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2010-05-25 US claimed
US-20070066502-A1 comprising 0.05 to 5% wt of a fluoride source, 40 to 95% wt of a solvent mixture comprising a polyhydric alcohol and an ether, 5 to 50% wt water, and a pH adjuster chosen from carbonic acid or its salt and a polycarboxylic acid and a base, where the molar ratio of polycarboxylic acid to the base is 1:1 ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-03-22 US claimed
EP-1755003-A1 Stripper Rohm and Haas Electronic Materials LLC (US) 2007-02-21 EP claimed