Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500985 | 1.00 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL25645589 | 1.00 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| Hydrochloric Acid SCHEMBL26984300 | 0.98 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL24364274 | 0.82 | PRCP (0.40) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL24233795 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL30471218 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL14359968 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL17066472 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL17987646 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2GBA1PRCP | |
| SCHEMBL24233804 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2GBA1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |