Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.69 |
| ▸ | HSP90AB1 | P08238 | 12/20 | 0.69 |
| ▸ | TRAP1 | Q12931 | 5/20 | 0.69 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.69 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16569779 | 0.92 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL16569852 | 0.91 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL3465002 | 0.90 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL20223358 | 0.89 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL16569684 | 0.89 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL21889014 | 0.88 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL18417665 | 0.88 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL18460288 | 0.87 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL22341555 | 0.86 | HSP90AB1 (0.61) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 | |
| SCHEMBL22507079 | 0.86 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1TRAP1ERBB2HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3086792-B1 | METHODS AND REAGENTS FOR RADIOLABELING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2022-10-12 | — | — | EP | disclosed |
| US-10828315-B2 | Targeted therapeutics | MADRIGAL PHARMACEUTICALS, INC. (US) | 2020-11-10 | — | — | US | disclosed |
| US-9994573-B2 | Methods and reagents for radiolabeling | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170056510-A1 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2017-03-02 | — | — | US | disclosed |
| EP-3086792-A1 | METHODS AND REAGENTS FOR RADIOLABELING | Memorial Sloan-Kettering Cancer Center (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015138039-A1 | METHODS AND REAGENTS FOR RADIOLABELING | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2015-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828315-B2 | Targeted therapeutics | CDC37, HSP90AB1, HSP90B1 | HSP90AA1 5/4885HSP90AB1 2/4885TRAP1 4/4885 |
| US-20170056510-A1 | TARGETED THERAPEUTICS | CDC37, HSP90AB1, HSP90B1 | HSP90AA1 5/4885HSP90AB1 2/4885TRAP1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.