Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170738 | 1.00 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| SCHEMBL6980945 | 0.88 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| SCHEMBL6980943 | 0.88 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| Hydrochloric Acid SCHEMBL7589497 | 0.87 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| Hydrochloric Acid SCHEMBL7591989 | 0.87 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| SCHEMBL19283462 | 0.85 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| SCHEMBL13450005 | 0.84 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2PRCPLMNA | |
| Oxalic Acid SCHEMBL7595700 | 0.82 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2LMNACHRNA7 | |
| Oxalic Acid SCHEMBL7595702 | 0.82 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2LMNACHRNA7 | |
| SCHEMBL20983529 | 0.82 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2PRCPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |