Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708320 | 0.96 | FFAR1 (0.38) | FFAR1ALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL1708196 | 0.87 | FFAR1 (0.54) | FFAR1 | |
| SCHEMBL3719338 | 0.85 | FFAR1 (0.37) | FFAR1ALDH1A1MAPTMAPK1CD274 | |
| SCHEMBL1708449 | 0.84 | FFAR1 (0.38) | FFAR1HRH3 | |
| SCHEMBL3718225 | 0.84 | FFAR1 (0.37) | FFAR1ALDH1A1MAPTMAPK1CD274 | |
| SCHEMBL1708205 | 0.84 | FFAR1 (0.38) | FFAR1CD274 | |
| SCHEMBL1708589 | 0.83 | FFAR1 (0.44) | FFAR1ALDH1A1MAPTMAPK1CD274 | |
| SCHEMBL1707839 | 0.83 | EPHX2 (0.45) | FFAR1 | |
| SCHEMBL3719197 | 0.83 | FFAR1 (0.35) | FFAR1ALDH1A1MAPTMAPK1CD274 | |
| SCHEMBL1708319 | 0.82 | FFAR1 (0.51) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |