Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550405 | 1.00 | AKR1C3 (0.47) | AKR1C3KMT2AMEN1TSHRLMNA | |
| SCHEMBL550406 | 1.00 | AKR1C3 (0.47) | AKR1C3KMT2AMEN1TSHRLMNA | |
| SCHEMBL550502 | 0.89 | AKR1C3 (0.46) | AKR1C3KMT2AMEN1TSHRLMNA | |
| SCHEMBL550501 | 0.89 | AKR1C3 (0.46) | AKR1C3KMT2AMEN1TSHRLMNA | |
| SCHEMBL17081996 | 0.89 | AKR1C3 (0.46) | AKR1C3KMT2AMEN1TSHRLMNA | |
| SCHEMBL549552 | 0.89 | SMN1; SMN2 (0.41) | KMT2AMEN1TSHRLMNAFAAH | |
| SCHEMBL549553 | 0.89 | SMN1; SMN2 (0.41) | KMT2AMEN1TSHRLMNAFAAH | |
| SCHEMBL550452 | 0.88 | AKR1C3 (0.49) | AKR1C3KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL17082047 | 0.88 | AKR1C3 (0.49) | AKR1C3KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL550451 | 0.88 | AKR1C3 (0.49) | AKR1C3KMT2ATSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-B1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-09-16 | — | — | EP | disclosed |