Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570179 | 1.00 | GFER (0.38) | GFERPSMD14USP2MMP2HRH3 | |
| SCHEMBL4570178 | 0.91 | SMN1; SMN2 (0.41) | GFERPSMD14USP2MMP2HRH3 | |
| SCHEMBL17082127 | 0.88 | GFER (0.42) | GFERPSMD14USP2MMP2HRH3 | |
| SCHEMBL4570177 | 0.88 | GFER (0.42) | GFERPSMD14USP2MMP2HRH3 | |
| SCHEMBL4570034 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9AHSD11B1 | |
| SCHEMBL17082098 | 0.86 | PIK3CA (0.32) | HSD11B1 | |
| SCHEMBL4570182 | 0.86 | PIK3CA (0.32) | HSD11B1 | |
| SCHEMBL3706523 | 0.86 | GFER (0.42) | GFERPSMD14USP2MMP2HRH3 | |
| SCHEMBL3706526 | 0.86 | GFER (0.42) | GFERPSMD14USP2MMP2HRH3 | |
| SCHEMBL2698014 | 0.86 | GFER (0.42) | GFERPSMD14USP2MMP2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-B1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-09-16 | — | — | EP | disclosed |