SCHEMBL17083207

SCHEMBL17083207

CCCc1ccc(-c2ccc(-c3cc(F)c(C(F)(F)Oc4ccc5c(F)c(F)c(F)cc5c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
GRM2 Q14416 1/20 0.34
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
RARB P10826 3/20 0.31
RARA P10276 1/20 0.30
RARG P13631 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17719460 0.94 RARB (0.36) ALOX5APFEN1GRM2S1PR1S1PR3
SCHEMBL20202949 0.94 GRM2 (0.33) ALOX5APFEN1GRM2
SCHEMBL20202969 0.93 RARB (0.39) ALOX5APFEN1GRM2S1PR1S1PR3
SCHEMBL20202968 0.93 ALOX5AP (0.35) ALOX5APFEN1GRM2
SCHEMBL20202970 0.93 RARB (0.31) RARBRARARARG
SCHEMBL17083187 0.93 RARB (0.31) RARBRARARARG
SCHEMBL17075778 0.91 ALOX5AP (0.34) ALOX5APFEN1GRM2
SCHEMBL20202931 0.89 ALOX5AP (0.38) ALOX5APFEN1GRM2S1PR1S1PR3
SCHEMBL20202966 0.89 ALOX5AP (0.34) ALOX5APFEN1GRM2
SCHEMBL1813180 0.89 GRM2 (0.37) ALOX5APFEN1GRM2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
EP-2977428-B1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-05-02 EP disclosed
US-9725651-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-08-08 US disclosed
US-9725651-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-08-08 US disclosed
US-20160122650-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-05-05 US disclosed
US-20160122650-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-05-05 US disclosed
US-9315727-B2 Compound having fluorinated naphthalene structure and liquid crystal composition of the same DIC Corporation (Tokyo) (JP) 2016-04-19 US disclosed
US-20150259599-A1 COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF THE SAME DIC CORPORATION (JP) 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259599-A1 COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF THE SAME TNK1, CTNND1, FLI1 ALOX5AP 3554/4885FEN1 564/4885GRM2 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.