Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078807 | 0.88 | HDAC1 (0.61) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL17079050 | 0.87 | HDAC1 (0.62) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL20432676 | 0.87 | HDAC1 (0.62) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL17078939 | 0.83 | HDAC1 (0.77) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL20432860 | 0.83 | HDAC1 (0.77) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL20432842 | 0.82 | HDAC1 (0.49) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL20432669 | 0.82 | HDAC1 (0.78) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL17078677 | 0.82 | HDAC1 (0.78) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL17078922 | 0.82 | HDAC1 (0.78) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL20432893 | 0.82 | HDAC1 (0.78) | HDAC1HDAC6HDAC8HDAC4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |