Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565162 | 1.00 | USP30 (0.39) | USP30NPY5RKDM4ELMNAPDE3B | |
| SCHEMBL13564866 | 0.90 | KDM4E (0.37) | NPY5RKDM4ELMNA | |
| SCHEMBL17090019 | 0.90 | KDM4E (0.37) | NPY5RKDM4ELMNA | |
| SCHEMBL13439095 | 0.89 | NPY5R (0.40) | NPY5RKDM4ELMNA | |
| SCHEMBL11941125 | 0.89 | NPY5R (0.40) | NPY5RKDM4ELMNA | |
| SCHEMBL11935386 | 0.89 | NPY5R (0.40) | NPY5RKDM4ELMNA | |
| SCHEMBL13565030 | 0.88 | USP30 (0.39) | USP30KDM4ELMNAPDE3BPDE3A | |
| SCHEMBL17090016 | 0.87 | NPY5R (0.37) | NPY5R | |
| SCHEMBL13565567 | 0.87 | NPY5R (0.37) | NPY5R | |
| SCHEMBL17090168 | 0.84 | MAPT (0.42) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |