Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 12/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565271 | 1.00 | NPY5R (0.35) | NPY5RGRIA2CYP3A4CYP2C8 | |
| SCHEMBL17090179 | 0.85 | GRIA2 (0.36) | NPY5RGRIA2 | |
| SCHEMBL14424634 | 0.80 | GRIA2 (0.39) | GRIA2 | |
| SCHEMBL10114891 | 0.80 | GRIA2 (0.39) | GRIA2 | |
| SCHEMBL11935455 | 0.79 | BTK (0.31) | — | |
| SCHEMBL13439197 | 0.79 | BTK (0.31) | — | |
| SCHEMBL17090434 | 0.77 | GRIA4 (0.46) | NPY5RGRIA2 | |
| SCHEMBL13565462 | 0.77 | GRIA4 (0.46) | NPY5RGRIA2 | |
| SCHEMBL11935136 | 0.76 | NPY5R (0.41) | NPY5RGRIA2CYP3A4CYP2C8 | |
| SCHEMBL11936151 | 0.76 | NPY5R (0.41) | NPY5RGRIA2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |