⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629087 | 1.00 | — | — | |
| SCHEMBL12450248 | 1.00 | — | — | |
| SCHEMBL1709034 | 1.00 | — | — | |
| SCHEMBL14226930 | 1.00 | — | — | |
| SCHEMBL12928668 | 1.00 | — | — | |
| SCHEMBL14629088 | 1.00 | — | — | |
| SCHEMBL12225583 | 1.00 | — | — | |
| SCHEMBL12928471 | 1.00 | — | — | |
| SCHEMBL27277795 | 0.77 | CYP2D6 (0.34) | — | |
| SCHEMBL24483924 | 0.75 | CA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627647-B1 | PROCESSES FOR PREPARATION OF LUBIPROSTONE | SCINOPHARM (KUNSHAN) BIOCHEMICAL TECH CO LTD (CN) | 2016-12-14 | — | — | EP | disclosed |
| US-8962688-B2 | Method for the treatment of gastrointestinal disorders | SUCAMPO AG (CH) | 2015-02-24 | — | — | US | disclosed |
| US-8962688-B2 | Method for the treatment of gastrointestinal disorders | SUCAMPO AG (CH) | 2015-02-24 | — | — | US | disclosed |
| US-20140315994-A1 | METHOD FOR TREATING GASTROINTESTINAL DISORDER | SUCAMPO AG (CH) | 2014-10-23 | — | — | US | disclosed |
| US-20140315994-A1 | METHOD FOR TREATING GASTROINTESTINAL DISORDER | SUCAMPO AG (CH) | 2014-10-23 | — | — | US | disclosed |
| US-8846958-B2 | Process for the preparation of lubiprostone | SCINOPHARM (KUNSHAN) BIOCHEMICAL TECHNOLOGY CO., LTD. (CN) | 2014-09-30 | — | — | US | disclosed |
| US-8846958-B2 | Process for the preparation of lubiprostone | SCINOPHARM (KUNSHAN) BIOCHEMICAL TECHNOLOGY CO., LTD. (CN) | 2014-09-30 | — | — | US | disclosed |
| US-20140235665-A1 | ANTI-CONSTIPATION COMPOSITION | SUCAMPO AG (CH) | 2014-08-21 | — | — | US | disclosed |
| US-20140235665-A1 | ANTI-CONSTIPATION COMPOSITION | SUCAMPO AG (CH) | 2014-08-21 | — | — | US | disclosed |
| US-8748481-B2 | Method for treating gastrointestinal disorder | SUCAMPO AG (CH) | 2014-06-10 | — | — | US | disclosed |
| US-20090030072-A1 | PHARMACEUTICAL COMBINATION OF OPIOID AND PROSTAGLANDIN COMPOUND | SUCAMPO AG (CH) | 2009-01-29 | — | — | US | disclosed |
| US-20090030072-A1 | PHARMACEUTICAL COMBINATION OF OPIOID AND PROSTAGLANDIN COMPOUND | SUCAMPO AG (CH) | 2009-01-29 | — | — | US | disclosed |
| US-20090012165-A1 | PHARMACEUTICAL COMBINATION OF NSAID AND PROSTAGLANDIN COMPOUND | SUCAMPO AG (CH) | 2009-01-08 | — | — | US | disclosed |
| US-20090012165-A1 | PHARMACEUTICAL COMBINATION OF NSAID AND PROSTAGLANDIN COMPOUND | SUCAMPO AG (CH) | 2009-01-08 | — | — | US | disclosed |
| US-7355064-B2 | Method for preparing 15-keto-prostaglandin E derivative | R-TECH UENO, LTD. (JP) | 2008-04-08 | — | — | US | disclosed |
| US-7355064-B2 | Method for preparing 15-keto-prostaglandin E derivative | R-TECH UENO, LTD. (JP) | 2008-04-08 | — | — | US | disclosed |
| US-20070276006-A1 | Method for the treatment of gastrointestinal disorders | SUCAMPO AG | 2007-11-29 | — | — | US | disclosed |
| US-20070276006-A1 | Method for the treatment of gastrointestinal disorders | SUCAMPO AG | 2007-11-29 | — | — | US | disclosed |
| US-20070185206-A1 | Method for preparing 15-keto-prostaglandin E derivative | R-TECH UENO, LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070185206-A1 | Method for preparing 15-keto-prostaglandin E derivative | R-TECH UENO, LTD. (JP) | 2007-08-09 | — | — | US | disclosed |