Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439238 | 0.84 | MAPK14 (0.39) | MAPK14PTGER4NPY5RCRHR1GRIA2 | |
| SCHEMBL11935496 | 0.84 | MAPK14 (0.39) | MAPK14PTGER4NPY5RCRHR1GRIA2 | |
| SCHEMBL13439240 | 0.83 | PTGER4 (0.43) | MAPK14PTGER4CRHR1L3MBTL1 | |
| SCHEMBL11935497 | 0.83 | PTGER4 (0.43) | MAPK14PTGER4CRHR1L3MBTL1 | |
| SCHEMBL10114945 | 0.82 | BRD4 (0.38) | NR3C1L3MBTL1KMT2AGRIA2 | |
| SCHEMBL13204428 | 0.82 | BRD4 (0.38) | NR3C1L3MBTL1KMT2AGRIA2 | |
| SCHEMBL13439181 | 0.80 | CREBBP (0.40) | MAPK14NR3C1NPY5RCRHR1L3MBTL1 | |
| SCHEMBL11935446 | 0.80 | CREBBP (0.40) | MAPK14NR3C1NPY5RCRHR1L3MBTL1 | |
| SCHEMBL13439247 | 0.80 | MAPK14 (0.48) | MAPK14PTGER4NR3C1NPY5RL3MBTL1 | |
| SCHEMBL10116138 | 0.79 | CCR8 (0.43) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |