SCHEMBL1709102

SCHEMBL1709102

C=C1C=CC(=S)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321045 0.73
SCHEMBL936459 0.61
SCHEMBL10103187 0.61
Methane SCHEMBL21611334 0.59
SCHEMBL11072942 0.58
SCHEMBL13819502 0.56 KDM4E (0.33)
SCHEMBL14480727 0.54
SCHEMBL1218300 0.54
SCHEMBL14040080 0.44
SCHEMBL7527260 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346752-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2023-11-02 US disclosed
US-20230346752-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2023-11-02 US disclosed
US-20230331767-A1 TARGETED STEROID COMPOUNDS PURDUE RESEARCH FOUNDATION 2023-10-19 US disclosed
US-20230293497-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION (US) 2023-09-21 US disclosed
US-20230293497-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION (US) 2023-09-21 US disclosed
US-11717514-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2023-08-08 US disclosed
US-11344623-B2 Cholecystokinin B receptor targeting for imaging and therapy PURDUE RESEARCH FOUNDATION (US) 2022-05-31 US disclosed
WO-2022094609-A1 OLIGONUCLEOTIDE-BASED THERAPEUTICS AND USES THEREOF SPEER TOD (US) 2022-05-05 WO disclosed
US-11318121-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2022-05-03 US disclosed
US-11219622-B2 Folate receptor binding conjugates of antifolates ENDOCYTE, INC. (US) 2022-01-11 US disclosed
WO-2008112873-A2 BINDING LIGAND LINKED DRUG DELIVERY CONJUGATES OF TUBULYSINS ENDOCYTE, INC. (US) 2008-09-18 WO disclosed
US-20080152702-A1 Releasable linkage and compositions containing same ZALIPSKY SAMUEL 2008-06-26 US disclosed
US-7390780-B2 Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification ALZA CORPORATION (US) 2008-06-24 US disclosed
EP-1880736-A1 Releasable linkage and composition containing same Alza Corporation (US) 2008-01-23 EP disclosed
US-7303760-B2 Method for treating multi-drug resistant tumors ALZA CORPORATION (US) 2007-12-04 US disclosed
US-7285622-B2 Releasable linkage and compositions containing same ALZA CORPORATION (US) 2007-10-23 US disclosed
US-7276248-B2 Conjugate having a cleavable linkage for use in a liposome ALZA CORPORATION (US) 2007-10-02 US disclosed
US-7238368-B2 Releasable linkage and compositions containing same ALZA CORPORATION (US) 2007-07-03 US disclosed
WO-2007022494-A2 MULTI-DRUG LIGAND CONJUGATES ENDOCYTE, INC. (US) 2007-02-22 WO disclosed
WO-2007022493-A2 LIGAND CONJUGATES OF VINCA ALKALOIDS, ANALOGS, AND DERIVATIVES ENDOCYTE, INC. (US) 2007-02-22 WO disclosed