Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.33 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709485 | 0.89 | PSEN1 (0.40) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL2315528 | 0.89 | PSEN1 (0.40) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL6918246 | 0.88 | PSEN1 (0.35) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL14108426 | 0.88 | PSEN1 (0.35) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL2317127 | 0.88 | PSEN1 (0.41) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL2317862 | 0.87 | PSEN1 (0.40) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL6917600 | 0.86 | PSEN1 (0.37) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL14108429 | 0.86 | PSEN1 (0.37) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL10032990 | 0.85 | PSEN1 (0.38) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL2315989 | 0.85 | PSEN1 (0.38) | DGAT1SOAT1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |