SCHEMBL170948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16990591	0.91	DDR2 (0.63)	DDR2RAF1MEN1KMT2AALDH1A1
	SCHEMBL169152	0.91	DDR2 (0.62)	DDR2RAF1MEN1KMT2ACSF1R
	SCHEMBL15574169	0.89	DDR2 (0.82)	DDR2RAF1MEN1KMT2AALDH1A1
	SCHEMBL13603537	0.88	RAF1 (0.72)	DDR2RAF1MEN1KMT2ACSF1R
	SCHEMBL13603518	0.86	DDR2 (1.00)	DDR2RAF1MEN1KMT2AALDH1A1
	SCHEMBL1662323	0.83	RAF1 (0.75)	DDR2RAF1MEN1KMT2ACSF1R
	SCHEMBL13648339	0.83	DDR2 (0.66)	DDR2RAF1MEN1KMT2AALDH1A1
	SCHEMBL15575225	0.82	DDR2 (0.83)	DDR2RAF1MEN1KMT2AALDH1A1
	SCHEMBL13603632	0.82	DDR2 (0.72)	DDR2RAF1MEN1KMT2AALDH1A1
	SCHEMBL15574740	0.81	DDR2 (0.71)	DDR2RAF1MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.