Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.46 |
| ▸ | PTPRB | P23467 | 15/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184920 | 0.89 | PTPRB (0.48) | CCR3PTPRBPTPN1 | |
| SCHEMBL16573541 | 0.84 | CCR3 (0.40) | CCR3PTPRBPTPN1 | |
| SCHEMBL467873 | 0.83 | PTPRB (0.41) | CCR3PTPRB | |
| SCHEMBL468061 | 0.83 | PTPRB (0.41) | CCR3PTPRB | |
| SCHEMBL14931760 | 0.82 | CCR3 (0.49) | CCR3PTPRBPTPN1 | |
| Bromide SCHEMBL19502581 | 0.82 | PTPRB (0.40) | CCR3PTPRB | |
| Bromide SCHEMBL467881 | 0.82 | PTPRB (0.40) | CCR3PTPRB | |
| SCHEMBL684296 | 0.81 | PTPRB (0.69) | CCR3PTPRB | |
| SCHEMBL468081 | 0.81 | PTPRB (0.69) | CCR3PTPRB | |
| SCHEMBL12944445 | 0.81 | PTPRB (0.55) | CCR3PTPRBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047966-A2 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | AKEBIA THERAPEUTICS INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2011005330-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | AKEBIA THERAPEUTICS INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010081172-A1 | METHODS FOR TREATING VASCULAR LEAK SYNDROME | AKEBIA THERAPEUTICS INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| WO-2008002570-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |