Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500711 | 0.91 | PTPRB (0.76) | PTPRB | |
| SCHEMBL500710 | 0.91 | PTPRB (0.76) | PTPRB | |
| SCHEMBL468284 | 0.90 | PTPRB (0.81) | PTPRB | |
| SCHEMBL468286 | 0.90 | PTPRB (0.81) | PTPRB | |
| SCHEMBL468274 | 0.90 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468276 | 0.90 | PTPRB (1.00) | PTPRB | |
| SCHEMBL500484 | 0.89 | PTPRB (0.73) | PTPRB | |
| SCHEMBL500485 | 0.89 | PTPRB (0.73) | PTPRB | |
| SCHEMBL684547 | 0.89 | PTPRB (0.82) | PTPRB | |
| SCHEMBL500468 | 0.88 | PTPRB (1.00) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047966-A2 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | AKEBIA THERAPEUTICS INC. (US) | 2012-04-12 | — | — | WO | disclosed |