Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 9/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246208 | 0.95 | SMYD2 (0.47) | SMYD2CHRM2CHRM3ADRB2 | |
| Sulfuric Acid SCHEMBL1245244 | 0.93 | SMYD2 (0.45) | SMYD2CHRM2CHRM3ADRB2 | |
| Trifluoroacetic Acid SCHEMBL6525747 | 0.92 | SMYD2 (0.46) | SMYD2CHRM2CHRM3ADRB2 | |
| SCHEMBL12847000 | 0.88 | SMYD2 (0.47) | SMYD2CHRM2CHRM3ADRB2 | |
| SCHEMBL12846797 | 0.87 | CHRM2 (0.45) | SMYD2CHRM2CHRM3ADRB2 | |
| SCHEMBL14576249 | 0.87 | SMYD2 (0.50) | SMYD2CHRM2CHRM3ADRB2 | |
| SCHEMBL12847130 | 0.86 | CHRM3 (0.44) | SMYD2CHRM2CHRM3ADRB2 | |
| SCHEMBL12846800 | 0.86 | CHRM2 (0.44) | SMYD2CHRM2CHRM3ADRB2 | |
| Trifluoroacetic Acid SCHEMBL6524593 | 0.85 | SMYD2 (0.46) | SMYD2CHRM2CHRM3ADRB2 | |
| SCHEMBL12847100 | 0.85 | CHRM2 (0.44) | SMYD2CHRM2CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119752-A1 | CHEMICAL COMPOUNDS | Astrazeneca AB (SE) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140527-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2015-09-24 | — | — | WO | disclosed |