Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430526 | 1.00 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2428455 | 0.91 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL17101610 | 0.90 | PTGDR2 (0.81) | PTGDR2 | |
| SCHEMBL17101627 | 0.90 | PTGDR2 (0.81) | PTGDR2 | |
| SCHEMBL17101613 | 0.90 | PTGDR2 (0.81) | PTGDR2 | |
| SCHEMBL2430611 | 0.89 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL14760884 | 0.88 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL14760680 | 0.88 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL14760679 | 0.88 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL17101626 | 0.88 | PTGDR2 (0.78) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301309-B2 | Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-05-28 | — | — | US | disclosed |
| US-10301309-B2 | Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-05-28 | — | — | US | disclosed |
| EP-3119779-B1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-07-11 | — | — | EP | disclosed |
| EP-3119779-B1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-07-11 | — | — | EP | disclosed |
| US-20180105520-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2018-04-19 | — | — | US | disclosed |
| US-20180105520-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2018-04-19 | — | — | US | disclosed |
| US-20180105520-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2018-04-19 | — | — | US | disclosed |
| US-9879006-B2 | Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators | IDORSIA PHARMACEUTICALS LTD | 2018-01-30 | — | — | US | disclosed |
| US-9879006-B2 | Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators | IDORSIA PHARMACEUTICALS LTD | 2018-01-30 | — | — | US | disclosed |
| US-9879006-B2 | Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators | IDORSIA PHARMACEUTICALS LTD | 2018-01-30 | — | — | US | disclosed |
| US-20170022196-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-01-26 | — | — | US | disclosed |
| EP-3119779-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd (CH) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015140684-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-09-24 | — | — | WO | disclosed |
| WO-2015140684-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022196-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | PTGDR, PTGDR2, PTGER2 | PTGDR2 2/4885 |
| US-10301309-B2 | Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators | PTGDR, PTGDR2, PTGER2 | PTGDR2 2/4885 |
| US-20180105520-A1 | AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | PTGDR, PTGDR2, PTGER2 | PTGDR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.