Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320651 | 0.86 | SCN9A (0.60) | SCN9ACYP2C9SCN1ASCN2ASCN8A | |
| SCHEMBL17270581 | 0.80 | SCN9A (0.37) | SCN9ACYP2C9SCN1ASCN2ASCN8A | |
| SCHEMBL17102711 | 0.80 | SCN9A (0.58) | SCN9ACYP2C9SCN1ASCN2ASCN8A | |
| SCHEMBL17270536 | 0.79 | SCN9A (0.41) | SCN9ACYP2C9SCN1ASCN2ASCN8A | |
| SCHEMBL319777 | 0.78 | SCN9A (0.55) | SCN9A | |
| SCHEMBL17270551 | 0.78 | SCN9A (0.34) | SCN9ACYP2C9SCN1ASCN2ASCN8A | |
| SCHEMBL17270568 | 0.77 | SCN9A (0.36) | SCN9ACYP2C9SCN1ASCN2ASCN8A | |
| SCHEMBL17270556 | 0.77 | SCN9A (0.37) | SCN9A | |
| SCHEMBL17270538 | 0.76 | SCN9A (0.47) | SCN9ACYP2C9SCN5A | |
| SCHEMBL17270531 | 0.76 | SCN9A (0.37) | SCN9ACYP2C9SCN1ASCN2ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145407-B2 | Sulfonamide compounds | PFIZER LIMITED (GB) | 2015-09-29 | — | — | US | disclosed |