Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654589 | 0.91 | PI4KB (0.65) | PI4KBKCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL653167 | 0.90 | PI4KB (0.75) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL655186 | 0.90 | PI4KB (0.61) | PI4KBALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL656634 | 0.88 | PI4KB (0.70) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL654434 | 0.87 | PI4KB (0.54) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL655537 | 0.86 | PI4KB (0.68) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL656541 | 0.86 | PI4KB (0.81) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL654471 | 0.85 | PI4KB (0.75) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL656564 | 0.85 | PI4KB (0.64) | PI4KBKCNH2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL654617 | 0.85 | PI4KB (0.66) | PI4KBALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2923734-A1 | Purine analogues and their use as immunosuppressive agents | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2015-09-30 | — | — | EP | disclosed |