Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534514 | 0.78 | PLK1 (0.57) | LMNARAB9AKMT2A | |
| SCHEMBL24534681 | 0.76 | HDAC1 (0.53) | EPHX2NR1H4HDAC6LMNARAB9A | |
| SCHEMBL24534839 | 0.76 | PLK1 (0.59) | RAB9AMEN1KMT2A | |
| SCHEMBL28456818 | 0.76 | POLB (0.57) | HDAC6RAB9AHDAC3HDAC8CA1 | |
| SCHEMBL4104833 | 0.74 | KMT2A (0.62) | EPHX2NR1H4MEN1KMT2A | |
| SCHEMBL24534804 | 0.74 | RARB (0.54) | MEN1CYP1A2KMT2A | |
| SCHEMBL10820422 | 0.73 | EPHX2 (0.55) | EPHX2NR1H4HDAC6LMNARAB9A | |
| Hydrochloric Acid SCHEMBL3883713 | 0.73 | KMT2A (0.61) | EPHX2NR1H4MEN1KMT2A | |
| SCHEMBL28788465 | 0.72 | SMN1; SMN2 (0.40) | LMNAMEN1CYP1A2KMT2A | |
| SCHEMBL10819627 | 0.72 | ST14 (0.47) | EPHX2NR1H4HDAC6RAB9ATPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450374-B9 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-11-23 | — | — | EP | disclosed |
| EP-2450374-B1 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2015-09-30 | — | — | EP | disclosed |