Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562711 | 1.00 | GRIN1 (0.45) | GRIN1GRIN2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6561158 | 0.99 | GRIN1 (0.44) | GRIN1GRIN2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6562366 | 0.89 | GRIN1 (0.47) | GRIN1GRIN2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7897054 | 0.89 | EPHX2 (0.44) | GRIN1GRIN2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7898530 | 0.89 | NPY4R (0.47) | SMN1; SMN2CPB2 | |
| SCHEMBL7898542 | 0.87 | NPY4R (0.47) | GRIN1GRIN2ASMN1; SMN2 | |
| SCHEMBL19165692 | 0.84 | C3AR1 (0.36) | GRIN1GRIN2ASMN1; SMN2EPHX2 | |
| SCHEMBL10277291 | 0.82 | EPHX2 (0.47) | GRIN1GRIN2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29421098 | 0.82 | MEN1 (0.44) | SMN1; SMN2EPHX2 | |
| SCHEMBL10650846 | 0.82 | MEN1 (0.44) | SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450374-B9 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-11-23 | — | — | EP | disclosed |
| EP-2450374-B1 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2015-09-30 | — | — | EP | disclosed |