Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484566 | 1.00 | SMPD3 (0.36) | SMPD3HRH3JAK3LCKGALR2 | |
| SCHEMBL17107358 | 0.89 | SMPD3 (0.39) | SMPD3HRH3SMARCA2SMARCA4PBRM1 | |
| SCHEMBL12485263 | 0.89 | SMPD3 (0.39) | SMPD3HRH3SMARCA2SMARCA4PBRM1 | |
| SCHEMBL17107357 | 0.89 | SMPD3 (0.36) | SMPD3HRH3JAK3LCKSMARCA2 | |
| SCHEMBL12485805 | 0.89 | SMPD3 (0.36) | SMPD3HRH3JAK3LCKSMARCA2 | |
| SCHEMBL12484038 | 0.88 | ADORA2A (0.38) | SMARCA2SMARCA4PBRM1NR1I2NR1H2 | |
| SCHEMBL12484034 | 0.88 | ADORA2A (0.38) | SMARCA2SMARCA4PBRM1NR1I2NR1H2 | |
| SCHEMBL12485353 | 0.87 | SYK (0.40) | HRH3JAK3LCKGALR2GALR1 | |
| SCHEMBL12485215 | 0.87 | GALR1 (0.39) | SMPD3HRH3JAK3GALR2GALR1 | |
| SCHEMBL12485127 | 0.87 | LCK (0.41) | HRH3JAK3LCKGALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | claimed |
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | SMPD3 2267/4885HRH3 50/4885JAK3 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.