Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17101233 | 0.89 | CTSA (0.51) | ADORA2AADORA1CTSAHPGDALDH1A1 | |
| SCHEMBL17101195 | 0.89 | CTSA (0.51) | ADORA2AADORA1CTSAHPGDALDH1A1 | |
| SCHEMBL17101459 | 0.89 | CTSA (0.51) | ADORA2AADORA1CTSAHPGDALDH1A1 | |
| SCHEMBL17101408 | 0.81 | CTSA (0.53) | CTSAHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17101248 | 0.78 | HPGD (0.45) | HPGDALDH1A1KDM4EHTT | |
| SCHEMBL17101507 | 0.77 | CTSA (0.47) | CTSAHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17101359 | 0.76 | CTSA (0.41) | CTSAHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17108621 | 0.75 | CTSA (0.46) | CTSAHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17108624 | 0.75 | CTSA (0.46) | CTSAHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20239111 | 0.75 | CTSA (0.52) | ADORA2AADORA1CTSAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015140527-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2015-09-24 | — | — | WO | disclosed |