Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17110666 | 0.87 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL17110578 | 0.86 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL17111173 | 0.85 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL29139381 | 0.85 | NTRK1 (0.74) | NTRK1NTRK3 | |
| SCHEMBL17110648 | 0.84 | NTRK1 (0.80) | NTRK1NTRK3 | |
| SCHEMBL18779377 | 0.84 | NTRK1 (0.88) | NTRK1NTRK3 | |
| SCHEMBL17110625 | 0.84 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL17110652 | 0.84 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL17111604 | 0.84 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL17110673 | 0.83 | NTRK1 (1.00) | NTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143654-A1 | TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2015-10-01 | — | — | WO | disclosed |