Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496455 | 0.86 | IDO1 (0.40) | DAOIDO1PDE2AKIF11NOTUM | |
| SCHEMBL21945440 | 0.81 | DAO (0.47) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL12603811 | 0.81 | DAO (0.51) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL5111503 | 0.79 | DAO (0.46) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL1972143 | 0.79 | DAO (0.46) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL5112247 | 0.79 | DAO (0.46) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL30617195 | 0.79 | DAO (0.46) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL18294991 | 0.79 | DAO (0.46) | DAORXRARXRBRXRGIDO1 | |
| SCHEMBL17864260 | 0.79 | IDO1 (0.58) | DAOIDO1PDE2ASLC6A4PTPN5 | |
| SCHEMBL17864251 | 0.79 | DAO (0.46) | DAORXRARXRBRXRGIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426122-A1 | Methylene urea derivative as RAF kinasse inhibitors | Merck Patent GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |