Phenyl Dihydrogen Phosphate

Phenyl Dihydrogen Phosphate

SCHEMBL1711873

Cc1nc2[nH]c(=O)[nH]c(=O)c2[nH]1.O=P(O)(O)Oc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.47
ADORA2B P29275 2/20 0.47
XDH P47989 3/20 0.39
PARP1 P09874 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
ADORA2A P29274 2/20 0.35
RAB9A P51151 2/20 0.35
BLM P54132 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP1A2 P05177 1/20 0.35
PABPC1 P11940 1/20 0.35
CYP2C19 P33261 1/20 0.35
CASP7 P55210 1/20 0.35
PMP22 Q01453 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA1 P30542 1/20 0.35
POLB P06746 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10997 0.76 MAPT (0.53) ADORA2BXDHPARP1KDM4EALDH1A1
Phenyl Dihydrogen Phosphate SCHEMBL28311333 0.69 SRC (1.00) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL20263 0.69 SRC (1.00) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL27269289 0.68 SRC (0.79) SRCALDH1A1BLMTDP1MAPT
Phenyl Dihydrogen Phosphate SCHEMBL27750193 0.68 SRC (0.79) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL27649540 0.68 SRC (0.79) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL28710502 0.67 SRC (0.86) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL23581620 0.67 SRC (0.95) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL9501417 0.67 SRC (0.95) SRCKDM4EALDH1A1BLMTDP1
Phenyl Dihydrogen Phosphate SCHEMBL9065420 0.67 SRC (0.95) SRCKDM4EALDH1A1BLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344126-A1 METHOD FOR TREATMENT OF COPD AND OTHER PULMONARY DISEASES Activaero GmbH (DE) 2011-07-20 EP disclosed
WO-2010043981-A1 METHOD FOR TREATMENT OF COPD AND OTHER PULMONARY DISEASES ACTIVAERO GMBH (DE) 2010-04-22 WO disclosed
US-20100092397-A1 Method For Treatment of COPD and Other Pulmonary Diseases ACTIVAERO GMBH (DE) 2010-04-15 US disclosed