Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291632 | 0.85 | KCNH2 (0.38) | KCNH2SLC2A1 | |
| SCHEMBL1722989 | 0.85 | KCNH2 (0.38) | KCNH2SLC2A1 | |
| SCHEMBL1711923 | 0.81 | SLC2A1 (0.38) | KCNH2SLC2A1 | |
| SCHEMBL2294713 | 0.81 | KCNH2 (0.36) | KCNH2SLC2A1 | |
| SCHEMBL1723020 | 0.81 | KCNH2 (0.36) | KCNH2SLC2A1 | |
| SCHEMBL22838577 | 0.79 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| SCHEMBL3427897 | 0.78 | KCNH2 (0.36) | KCNH2SLC2A1 | |
| SCHEMBL1722990 | 0.77 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL1722995 | 0.77 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL24837299 | 0.76 | KCNH2 (0.41) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344495-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010041194-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-15 | — | — | WO | disclosed |