Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20678139 | 1.00 | HSD17B10 (0.36) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| Bromide SCHEMBL5126215 | 0.97 | PLA2G10 (0.34) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL5665370 | 0.97 | HSD17B10 (0.38) | HSD17B10CACNA1HSMN1; SMN2GLATP53 | |
| SCHEMBL15938241 | 0.90 | GLA (0.43) | PLA2G10PLA2G5CACNA1HSMN1; SMN2GLA | |
| SCHEMBL20678135 | 0.90 | GLA (0.43) | PLA2G10PLA2G5CACNA1HSMN1; SMN2GLA | |
| SCHEMBL10063507 | 0.90 | HSD17B10 (0.42) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL1041478 | 0.90 | HSD17B10 (0.42) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL16749946 | 0.90 | HSD17B10 (0.42) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL20260416 | 0.90 | HSD17B10 (0.42) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL12004645 | 0.90 | HSD17B10 (0.42) | HSD17B10PLA2G10PLA2G5CACNA1HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190142977-A1 | GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF Zn2+ WITH MRI | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-05-16 | — | — | US | disclosed |
| US-20170106103-A1 | NEW GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF Zn2+ WITH MRI | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-04-20 | — | — | US | disclosed |
| US-20170106103-A1 | NEW GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF Zn2+ WITH MRI | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-04-20 | — | — | US | disclosed |
| WO-2015142583-A1 | NEW GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF ZN2+ WITH MRI | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142977-A1 | GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF Zn2+ WITH MRI | SLC30A6, SLC30A7, SLC39A11 | HSD17B10 4645/4885PLA2G10 1577/4885PLA2G5 1648/4885 |
| US-20170106103-A1 | NEW GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF Zn2+ WITH MRI | SLC30A6, SLC30A7, SLC39A11 | HSD17B10 4668/4885PLA2G10 1075/4885PLA2G5 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.