Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575645 | 1.00 | FOLH1 (0.75) | FOLH1 | |
| SCHEMBL19403116 | 0.99 | FOLH1 (0.73) | FOLH1 | |
| SCHEMBL1518023 | 0.98 | FOLH1 (0.73) | FOLH1 | |
| SCHEMBL16781668 | 0.98 | FOLH1 (0.73) | FOLH1 | |
| SCHEMBL25574479 | 0.97 | FOLH1 (0.71) | FOLH1 | |
| SCHEMBL16781666 | 0.97 | FOLH1 (0.71) | FOLH1 | |
| SCHEMBL23671927 | 0.95 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL23671926 | 0.95 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL23790343 | 0.94 | FOLH1 (0.67) | FOLH1 | |
| SCHEMBL18655464 | 0.94 | FOLH1 (0.70) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466928-A1 | LABELED INHIBITORS OF PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA), BIOLOGICAL EVALUATION, AND USE AS IMAGING AGENTS | The Johns Hopkins University (US) | 2019-04-10 | — | — | EP | disclosed |
| US-10039845-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA) biological evaluation, and use of imaging agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180085478-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) BIOLOGICAL EVALUATION, AND USE OF IMAGING AGENTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-03-29 | — | — | US | disclosed |
| US-9694091-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA) biological evaluation, and use of imaging agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2921482-A2 | Labeled inhibitors of prostate-specific membrane antigen (PSMA), biological evaluation, and use as imaging agents | The Johns Hopkins University (US) | 2015-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085478-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) BIOLOGICAL EVALUATION, AND USE OF IMAGING AGENTS | FOLH1, KLK3, PHOSPHO1 | FOLH1 1/4885 |
| US-10039845-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA) biological evaluation, and use of imaging agents | FOLH1, KLK3, PHOSPHO1 | FOLH1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.