Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.78 |
| ▸ | WNT1 | P04628 | 13/20 | 0.78 |
| ▸ | CLK2 | P49760 | 2/20 | 0.72 |
| ▸ | CLK3 | P49761 | 2/20 | 0.72 |
| ▸ | GSK3B | P49841 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17095563 | 0.88 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17095854 | 0.85 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17095971 | 0.84 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL6219544 | 0.84 | DYRK1A (0.72) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17095496 | 0.84 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL20125806 | 0.83 | DYRK1A (0.71) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17096031 | 0.83 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17095758 | 0.81 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17096785 | 0.81 | DYRK1A (0.78) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL17095451 | 0.81 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143380-A1 | 5-SUBSTITUTED INDAZOLE-3-CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED, LLC (US) | 2015-09-24 | — | — | WO | disclosed |