SCHEMBL17122008

SCHEMBL17122008

O=C1OC(=O)C2=C1CC(Br)C(Br)C2

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10775834 1.00 TSHR (0.38) TSHR
SCHEMBL9315572 0.84 TSHR (0.31) TSHR
SCHEMBL17195928 0.73
SCHEMBL7112796 0.72 CRBN (0.42) TSHR
SCHEMBL7283621 0.72 SMN1; SMN2 (0.38) TSHR
SCHEMBL5909229 0.70 FNTA (0.33) TSHR
SCHEMBL9315860 0.68
SCHEMBL22743527 0.67
SCHEMBL55174 0.65
SCHEMBL3400665 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2924053-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID COMPOUND OR SALT THEREOF Glytech, Inc. (JP) 2015-09-30 EP disclosed