SCHEMBL171224

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13603568	0.94	DDR2 (0.47)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL171401	0.92	DDR2 (0.55)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL16990653	0.90	FLT1 (0.48)	DDR2KDRMCHR1HTR2AFLT1
	SCHEMBL171252	0.89	DDR2 (0.54)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL15575261	0.89	DDR2 (0.55)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL5569661	0.88	GSK3B (0.60)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL171352	0.88	DDR2 (0.65)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL15573142	0.86	RAF1 (0.44)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL13648366	0.86	GSK3B (0.48)	DDR2GSK3BMAPK14KDRRAF1
	SCHEMBL170869	0.86	DDR2 (0.53)	DDR2GSK3BMAPK14KDRRAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.