Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | GLA | P06280 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17122659 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL29605359 | 0.87 | KDM4E (0.72) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL28773386 | 0.87 | KDM4E (0.72) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122603 | 0.87 | KDM4E (0.66) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122731 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122700 | 0.86 | KDM4E (0.77) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122644 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122611 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122640 | 0.85 | KDM4E (0.78) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL17122638 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1HPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2924037-A1 | QUINAZOLINE DERIVATE AND USE THEREOF AS APOPTOSIS INHIBITOR | Linx Pharmaceutical Co., Ltd. (CN) | 2015-09-30 | — | — | EP | disclosed |