SCHEMBL17124128

SCHEMBL17124128

c1ccc2c(-c3ccc4c(c3)c3cccnc3n4-c3ccc4ccc5cccnc5c4n3)nccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.35
CCR1 P32246 5/20 0.34
CCR8 P51685 5/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 3/20 0.34
CCR5 P51681 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 2/20 0.34
TSHR P16473 2/20 0.34
GMNN O75496 1/20 0.34
TP53 P04637 1/20 0.34
HSP90AA1 P07900 1/20 0.34
MMP2 P08253 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MMP9 P14780 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
MMP8 P22894 1/20 0.34
THPO P40225 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17124081 0.87 MAPT (0.36) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124112 0.87 TSHR (0.38) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124138 0.87 TSHR (0.38) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124139 0.85 TSHR (0.36) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124086 0.85 IRAK4 (0.36) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124082 0.85 TSHR (0.41) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124129 0.84 CCR1 (0.37) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124077 0.84 TSHR (0.36) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124116 0.83 CCR1 (0.34) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17124076 0.83 NPY5R (0.34) CCR1CCR8KDM4EMAPTCCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290814-B2 Organic light-emitting diode LG DISPLAY CO., LTD. (KR) 2019-05-14 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280141-A1 ORGANIC LIGHT-EMITTING DIODE LG DISPLAY CO., LTD. (KR) 2015-10-01 US disclosed