Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959364 | 1.00 | NR1H4 (0.82) | NR1H4 | |
| SCHEMBL17128561 | 1.00 | NR1H4 (0.82) | NR1H4 | |
| SCHEMBL19189636 | 1.00 | NR1H4 (0.82) | NR1H4 | |
| SCHEMBL19189922 | 0.91 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL17128588 | 0.91 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL17128590 | 0.91 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL9960085 | 0.91 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL19739533 | 0.90 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL17128505 | 0.90 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL17128508 | 0.90 | NR1H4 (1.00) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150568-B2 | Compositions and methods for modulating FXR | NOVARTIS AG (CH) | 2015-10-06 | — | — | US | disclosed |