Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490590 | 0.83 | MEN1 (0.44) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL171515 | 0.82 | KDM1A (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1MEN1 | |
| SCHEMBL13490575 | 0.81 | MEN1 (0.44) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13490572 | 0.81 | P2RY12 (0.43) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13490589 | 0.80 | MEN1 (0.42) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL14544111 | 0.79 | GRIN2B (0.41) | RAB9ASMN1; SMN2NPC1KDM4EMEN1 | |
| SCHEMBL169438 | 0.79 | MEN1 (0.41) | RAB9ASMN1; SMN2NPC1MAPTATM | |
| SCHEMBL169428 | 0.79 | GRM5 (0.50) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL171543 | 0.78 | GRIN2B (0.42) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13592762 | 0.77 | MEN1 (0.40) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |