Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | P4HB | P07237 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | GRK6 | P43250 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700877 | 0.92 | RCE1 (0.74) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL1700904 | 0.84 | RCE1 (0.71) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL14907845 | 0.82 | RCE1 (0.71) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL17131850 | 0.81 | RCE1 (0.67) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL17131892 | 0.80 | RCE1 (0.76) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL17131902 | 0.80 | KDM4E (0.68) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL17131833 | 0.78 | KDM4E (0.74) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL23359134 | 0.77 | RCE1 (1.00) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL31741895 | 0.77 | RCE1 (1.00) | RCE1ALDH1A1TP53CYP3A4CYP2C9 | |
| SCHEMBL31741894 | 0.77 | RCE1 (1.00) | RCE1ALDH1A1TP53CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150272939-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase | YALE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| US-20150272939-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase | YALE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272939-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase | KDM1B, KDM1A, JMJD1C | RCE1 1022/4885ALDH1A1 1314/4885TP53 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.