Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 20/20 | 1.00 |
| ▸ | GBA2 | Q9HCG7 | 20/20 | 1.00 |
| ▸ | GBA1 | P04062 | 19/20 | 1.00 |
| ▸ | LCT | P09848 | 12/20 | 1.00 |
| ▸ | SI | P14410 | 9/20 | 1.00 |
| ▸ | MGAM | O43451 | 6/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nizubaglustat SCHEMBL17132915 | 1.00 | UGCG (1.00) | UGCGGBA2GBA1LCTSI | |
| Nizubaglustat SCHEMBL17132922 | 1.00 | UGCG (1.00) | UGCGGBA2GBA1LCTSI | |
| Nizubaglustat SCHEMBL17132924 | 1.00 | UGCG (1.00) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL25962102 | 0.89 | UGCG (0.80) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL19224234 | 0.89 | UGCG (0.79) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL19224235 | 0.89 | UGCG (0.79) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL20862311 | 0.89 | UGCG (0.79) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL19224258 | 0.88 | UGCG (1.00) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL17132965 | 0.88 | UGCG (1.00) | UGCGGBA2GBA1LCTSI | |
| SCHEMBL17132917 | 0.88 | UGCG (1.00) | UGCGGBA2GBA1LCTSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015147639-A1 | N-(5-((ARYL OR HETEROARYL)METHYLOXY)PENTYL)-SUBSTITUTED IMINOSUGARS AS INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | ACADEMISCH MEDISCH CENTRUM (NL) | 2015-10-01 | — | — | WO | disclosed |